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Senior Upstream Scientist

Experience Dependant
Job Reference: J5633304
Updated On: 21/05/2020
Status: Open to Applications
Hyper Recruitment Solutions
Sectors: Pharmaceutical, Biotechnology, Cell & Gene Therapy, Bioprocessing, Science

Skills: Biochemistry - Fermentation / USP, Biochemistry - Production / Manufacturing, Life Sciences - Cellular Biology, Life Sciences - Molecular Biology

Job Information

Role Overview

We are currently looking for a Senior Upstream Scientist to join a leading biopharmaceutical company based in the Berkshire area. As the Senior Scientist you will be joining the Upstream Process Development Team, focusing your work on microbial upstream process development and plasmid production.

Key Duties and Responsibilities

Your duties as the Senior Upstream Scientist will be varied however the key duties and responsibilities are as follows:

1. You will develop microbial upstream processes for plasmid DNA production as an input into gene therapy products

2. As the Senior Upstream Scientist, you will be responsible for identifying scale-up challenges and developing robust upstream processes for tech transfer to manufacturing scale, as well as developing and optimising efficient microbial fermentation, lysis and primary recovery steps

3. You will work with equipment of varying levels, including shake flasks, ambr250, 5L and 200L scales

4. It will be your responsibility to evaluate equipment improvements for automation and process operations and sampling

Role Requirements

To be successful in your application to this exciting opportunity as the Senior Upstream Scientist, we are looking to identify the following on your profile and past history:

1. Essentially, you will have a relevant degree in a biochemistry related subject (e.g. biochemical engineering, biotechnology, cellular biology, biochemistry, molecular biology, etc) and a PhD is highly desirable

2. Proven industry experience in an upstream process development setting, working with bioreactors and fermenters is necessary

3. A working knowledge and practical experience with primary recovery operations for the development of plasmid DNA or biologics products is required

Key Words: Upstream | Senior Scientist | Fermentation | Microbial | Bioreactor | Ambr | Production | Plasmid | DNA | Biochemistry | Biologics | Biopharmaceutical | Biochemical Engineering | Process Development | Gene Therapy | AAV | Manufacturing | USP
Georgina Beer
Your Recruitment ConsultantGeorgina
DisclaimerHyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer who are certified by Investors in People for our talent development. We welcome applications for any applicant who fulfil the role requirements for this position. HRS is a company exclusively supporting the science and technology sectors, and is made up of a collaboration of recruitment processionals and scientists. We look forward to helping you with your next career moves.